Pharmaceutical Intermediates Anti-Depression Raw Powder Tianeptine Hemisulfate Monohydrate (THM) CAS 1224690-84-9 Product name:Tianeptine Sulfate |
Other Name: Tianeptine Sodium Salt,Tianeptine Hemisulfate Monohydrate (THM) |
Appearance:White Powder |
CAS:1224690-84-9 |
M.F.:C42H56Cl2N4O14S3 |
M.W.:1008.01344 |
Specification:99% |
Tianeptine sodium salt is a salt of Tianeptine. Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT (serotonin;sc-201146) uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake .
Tianeptine sodium salt is a prescription medication used to treat depression in all its ranges of severity. The tianeptine medication is generally described as a tricyclic antidepressant. This is a chemical compound so named because it contains three rings of atoms. Like other tricyclic antidepressants, tianeptine blocks the reuptake, or re-absorption, of serotonin. This is a neurotransmitter responsible for one's sense of well-being. The reuptake consequently increases the availability of such substances to the brain.
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Tianeptine hemisulfate monohydrate (THM) | 1224690-84-9 | 99% |
J-147 | 1146963-51-0 | 99% |
ITEM | SPECIFICATION | RESULT | METHOD |
Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
Specific Optical | -2.4°~ -2.8° | -2.72° | |
Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
pH | 4.5~7.0 | 5.10 | |
Related substance | Spot not bigger than standard solution spot | No spot | TLC |
Water Content | ≤2% | 0.26% | KF |
Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
1) Tianeptine Improves Depressive Symptoms
2) Tianeptine Lessens Anxiety, Stress, and PTSD and Symptoms From Stress.
3) Tianeptine Benefits Memory and Learning
4) Tianeptine is an Anti-inflammatory
5) Tianeptine decreases pain
6) Tianeptine Helps Treat Irritable bowel Syndrome
7) Tianeptine Reduces Asthma
Tianeptine is antidepressant. The animal has: the hippocampus pyramidal cells increased spontaneous activity, and accelerating its function was inhibited after recovery; increase in cortical and hippocampal neurons at sites of 5- serotonin reuptake. Tianeptine without following adverse effects: sleep and alertness; cardiovascular system; cholinergic system ( without anticholinergic symptoms ); drug craving.
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