China Good Quality Price Powder Docetaxel Anhydrous CAS: 114977-28-5, Find details about China Docetaxel Anhydrous, CAS114977-28-5 from Good Quality Price Powder Docetaxel Anhydrous CAS: 114977-28-5
Product name | Docetaxel |
Specification | In house |
CAS | 114977-28-5 |
Stock | Fresh |
Molecular Structure |
|
Molecular Formula | C43H53NO14 |
Molecular Weight | 807.88 |
2. Description
Items | The Standard Result |
Appearance | White to almost white crystalline Powder, odourless, slightly hygroscopic |
Assay | 98.0%~102.0% |
Water | 3.0% Max |
Arsenic | 0.00015% Max |
Sulfate | 0.01% Max |
Heavy metals | 10ppm Max |
Bacterial endotoxins | Less than 0.3IU/mg |
TAMC | NMT 100CFU/g |
TYMC | NMT 10CFU/g |
3. Function and Usage
Docetaxel (XT) sold as Taxotere or Docecad, is a well-established anti-mitotic chemotherapy medication that works by interfering with cell division. Docetaxel is approved by the FDA for treatment of locally advanced or metastatic breast cancer, head and neck cancer, gastric cancer, hormone-refractory prostate cancer and non small-cell lung cancer. Docetaxel can be used as a single agent or in combination with other chemotherapeutic drugs as indicated depending on specific cancer type and stage.
Docetaxel is a member of the taxane drug class, which also includes the chemotherapeutic medication paclitaxel. Although docetaxel remains twice as potent as paclitaxel (due to docetaxel's effect on the centrosome of the mitotic spindle), the two taxanes have been observed to have comparable efficacy. Several recent articles have found "no evidence that regimens containing docetaxel yield greater benefits than those including paclitaxel." While efficacy between the two agents has been observed to be equivalent, paclitaxel may cause fewer side effects. Additionally, it has been noted that docetaxel is prone to cellular drug resistance via a variety of different mechanisms.
4.Packing and shippment
Contact Information
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