China High Purity 98% Polysaccharide Pullulan for Pharmaceutic Adjuvant as Adhesion Agent and Film-Forming Agent and Capsule CAS 9057-02-7, Find details about China Pullulan, Pharmaceutic Adjuvant from High Purity 98% Polysaccharide Pullulan for Pharmaceutic Adjuvant as Adhesion Agent and Film-Forming Agent and Capsule CAS 9057-02-7
2. Solubility. Pullulan polysaccharide can be dissolved in water, dissolution rate than carboxymethyl cellulose, sodium alginate, polypropylene alcohol, polyvinyl alcohol more than two times faster, the solution is neutral, no ionization, no gelation, no crystallization. Different water temperatures have little effect on the dissolution properties of Pullulan, so the dissolution temperature range of pullulan is wide (0~100ºC).
3.Stability. The molecules of Pullulan have linear structure, so compared with other polysaccharides, the aqueous solution of Pullulan is less viscous and does not form colloid. It is a neutral solution with strong adhesion. Pullulan contains almost no reducing group and only produces weak intermolecular forces with other molecules. When the pH value is below 2.5, if heated for a long time, it will partially decompose like other polysaccharides, resulting in a decrease in the viscosity of the solution.
4. Acid and alkaline resistance. Pullulan is acid-resistant but not alkali-resistant, and its pH tolerance ranges from 2.5 to 9.5.
5. Stickiness.Pullulan polysaccharide has strong viscosity. This characteristic is used in a wide range of pharmaceutical products, such as tablet adhesives and film adhesives for wound healing sites.
6. Membrane forming. Pullulan has excellent membrane forming Pullulan membrane is 10 times higher than gelatin, 10 times higher than cellophane, 30 times higher than PVDC, It is 80 times higher than LDPE(low density polyethylene) and 200 times higher than HPMC. Pure Pullulan polysaccharide film can isolate air and water molecules, etc. When pullulan polysaccharide is mixed with other substances, it can adjust the air insulation after forming the film. In addition, the Pullulan capsule has a high tensile strength.
7.Protective agent.After forming the membrane, pullulan polysaccharide can well protect the contents of its coating from oxidation and volatilization, prolong the action time of the active components, and the membrane also has a certain ability of ultraviolet resistance. After forming pullulan film, under the dry condition of the surface, it also can prevent bacteria and other infiltration. This characteristic of Pullulan is widely used in medicinal capsule shell, wettable medical bandage, animal protection, cosmetics, food film protection and other fields.
8.Decompose. Pullulan at over 250 degrees Celsius. In the natural environment, the right conditions (temperature, moisture, air), can be degraded by bacteria. Belongs to the green environmental protection natural material.