Basic Info.
SR9011
CAS No.: 1379686-29-9
Molecular formular: C20H24ClN3O4S
Appearance: White powder
Purity: 99%
Application: SR9011 increase exercise endurance and loss weight.
Usage:reduce mass fat
Description:
SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates.
    SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.
    SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases. 
Application:
In vitro: SR9011 was used at 5-10 μM concentration in vitro and in cellular assays.
In vivo: IP administration of SR9011 was used at 100 mg/kg once or twice per day for 12-30 days in different mouse models.

Function:
1. 1/3 as androgenic as test in muscle tissue
2. Anabolic at doses above 50mg
3. Great for strength
4. Great for muscle hardness
5. Great for enhanced vascularity
6. Great for endurance (aerobic or anaerobic)
7. Accelerated fat loss above 50mg
8. Joint healing effects

 

Product Name	SR9011
Appearance	White Powder
CAS	1379686-29-9
Grade Standard	Medicine grade
Purity:	99%

Introduction:

SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates. SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended. SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism.
 
Function:
Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure.

SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia.

Description:
SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates. SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB- with an EC50 ~790 nM and REV-ERB-with EC50 ~560 nM. 
   It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB- and REV-ERB- play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure.
   Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
 

Company Profile

 

Hjtc (Xiamen) Industry Co., Ltd.  is a professional new-typeSupplier of the Pharmaceutical Packaginga &Steroids Raw Materials .It's factory founded in July 2014 by a group overseas PhD and experienced commercial professionals in Hubei,China. Biocar committed to emerge as a leading of manufacturing, marketing and CMO service of Active Pharmaceutical Ingredients,Intermediates and Herb Extract for global life Science Companies.we have established close and stable cooperative relationship with over 420 manufacturers with long-term with consistent suppliers at India and China.Our mission is to bring products to markets in the most effective & efficient way in terms of high value and quality.Our exports reach more than 105 countries through branches, subsidiaries and distribution network spread across the South Asia, North America ,South America and MEA.Our focus is to add value to the global pharmaceutical industry by serving as a reliable partner.

 

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Name	CasNO.	packaging
HCG 5000iu		5000iu/vial
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Name	CasNO.	packaging
CJC1295 DAC(CJC1295 with DAC)		2mg/vial
CJC1295 (CJC1295 without DAC)		2mg/vial
BPC157		5mg/vial
GHRP-2	158861-67-7	5mg/vial
GHRP-2	158861-67-7	10mg/vial
GHRP-6	87616-84-0	5mg/vial
GHRP-6	87616-84-0	10mg/vial
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MK2866	841205-47-8	> 99%
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GW501516	317318-70-0	> 99%
LGD4033	1165910-22-4	> 99%
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YK11	431579-34-9	> 99%
Andarine S4	401900-40-1	> 99%
SR9009	1379686-30-2	> 99%
SR9011	1379686-29-9	> 99%
S-23	1010396-29-8	> 99%
AICAR	2627-69-2	> 99%

 

Clients Feedback

 

Feed back from customers

 all received and signed for with no problems, I am very pleased with the product, very professional finish and nice hologram effect. Excellent work!

-- Don Johnson--UK

WOW WOW WOW!i am very very impressed with the quality and the prouduct you have made,you have gained a long term customer in me!

-- Mark Right--USA

I must say I'm really impressed. All label and box look amazing. A big thanks to you for your help. we will certainly do more busienss with A-source!

-- Rauk---Switzerland

Everything is ok. I am starting to filter oils and packing the Products next week. So hopefully there will be another order as soos as possible

-- Azucar--Spain

Well received parcel without problem,Good quality my partner said!

-- Micha michka---Netherlands

Hi the label are good and custom without problem,good job!

-- Simon--New Zealand

Thank you so much they were perfect, and box color was a little bit grey and it looks like much better very professional.

-- Steve--Armenia

Thank you for great jobs, label box with hologram are perfect, I am impressed! Plastic trays can suit for 2ml vial and box as well!

1.  Offer information for quotation;

2.  Confirm price and order;

3.  Design /sample approval

4.  70% deposit

5.  Mass production

6.  Show final product images

7.  Pay rest balance

8.  Shipping and send tracking number

9.  After-sales service;

Q1: Can I get some samples?
A: Sure, we offer free sample, you just need to pay the shipping cost.
 
Q2: How to make orders?
A: Please send inquiry to us, then we will do the offer. Payment via Western Union, Moneygram, Bank Account and Bitcoin. Then we will arrange shipping. After delivery we will offer tracking No..

Q3: Is the shipping 100% Guarantee?
A: Yes, we offer 100% Shipping Guarantee. If any seized parcel we will do resending. 

Q4: How to delivery?
A: Parcel will be shipped out in 3 working days after payment. Usually we use EMS, ePacket, Fedex, DHL, TNT and USA Domestic mixed shipping and so on. 
 
Q5: Is there any discount?
A:Yes. The price is negotiable. Just send us the items you need and the quantity. We will apply the best price and offer discount for you.
 
Q6: What is the Minimum order quantity?
A: Usually MOQ is 100g. But depends on the items and your requirements we also can do 10g, 20g, 30g or 50g.