China Professional Supply 99% High Purity Powder Favipiravir CAS 259793 -96-9

China Professional Supply 99% High Purity Powder Favipiravir CAS 259793-96-9, Find details about China 259793-96-9, Favipiravir from China Professional Supply 99% High Purity Powder Favipiravir CAS 259793-96-9

Basic Info.

Model NO.

259793-96-9

Wickr

Bellachen

Common Name

Favipiravir

CAS Number

259793-96-9

Molecular Weight

157.103

Density

1.6±0.1 g/cm3

Boiling Point

552.6±50.0 °c at 760 Mmhg

Molecular Formula

C5h4fn3o2

Flash Point

288.0±30.1 °c

Storage Temp.

Inert Atmosphere, 2-8°c

Pka

8.77±0.60(Predicted)

Trademark

Hanhong

Transport Package

Customized

Specification

Customized

Origin

China

Model NO.

259793-96-9

Wickr

Bellachen

Common Name

Favipiravir

CAS Number

259793-96-9

Molecular Weight

157.103

Density

1.6±0.1 g/cm3

Boiling Point

552.6±50.0 °c at 760 Mmhg

Molecular Formula

C5h4fn3o2

Flash Point

288.0±30.1 °c

Storage Temp.

Inert Atmosphere, 2-8°c

Pka

8.77±0.60(Predicted)

Trademark

Hanhong

Transport Package

Customized

Specification

Customized

Origin

China

Product Desciption

China Professional Supply 99% High Purity Powder Favipiravir CAS 259793-96-9

favipiravir Chemical Properties

density	1.78±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
pka	8.77±0.60(Predicted)

favipiravir Usage And Synthesis

History

Favipiravir is a broad-spectrum antiviral drug that was cleared by the Drugs Controller General of India (DCGI) last week for "emergency restricted" use among patients. Glenmark will sell the generic favipiravir under the brand name FabiFlu.
Favipiravir was originally developed in the late 1990s by a company that was later purchased by the Japanese firm Fujifilm as part of its transition from the photo business to healthcare. After being tested against a range of viruses, the drug was approved in Japan in 2014 for emergency use against flu epidemics or to treat new strains of influenza.

Mode of Action

Favipiravir inhibits the RNA-dependent RNA polymerase (RdRp) - an enzyme that allows the coronavirus to replicate inside host cells.Inside the cells, favipiravir is converted to favipiravir ribofuranosyl-5′-triphosphate (favipiravir-RTP) by host cells. This molecule then blocks the RdRp enzyme, the virus that causes.According to a statement by Glenmark, favipiravir works only during the earlier stages of the disease, when the viral replication is higher, but the body's immune response has not gone into overdrive.
Metabolism of favipiravir to its triphosphate form occurs in an extracellular environment in a concentration-dependent manner. The vRNA polymerase mistakenly recognizes favipiravir-RTP as a purine nucleotide. This favipiravir-RTP is misincorporated in nascent vRNA, or it may act by binding to conserved polymerase domains, preventing incorporation of nucleotides for vRNA replication and transcription (Jin et al., 2013).

China Professional Supply 99% High Purity Powder Favipiravir CAS 259793-96-9