China High Quality 99% Tofacitinib Citrate CAS 540737-29-9 with Best Price, Find details about China Rapamycin, Piracetam from High Quality 99% Tofacitinib Citrate CAS 540737-29-9 with Best Price
Product Name | Tofacitinib citrate |
Appearance | White to beige solid |
Assay | 99%min |
Test | HPLC |
Certificate | ISO 9001 |
CAS | 540737-29-9 |
MF | C16H20N6O.C6H8O7 |
MW | 504.497 |
Storage conditions | Sealed in dry, room temp |
Tofacitinib citrate is a king of drugs developed by the US pharmaceutical company for treating rheumatoid arthritis, for the treatment of methotrexate inadequate response or intolerance to severe active rheumatoid arthritis (RA) in adult patients. Tofacitinib citrate is approved for the treatment of methotrexate inadequate response or intolerance to severe active rheumatoid joints arthritis (RA) in adult patients.
(1).Tofacitinib citrate is an oral, small molecule drug used to treat adults with moderate-to-severe, active rheumatoid arthritis who have not responded well to being treated with methotrexate. Methotrexate is a disease-modifying antirheumatic drug (DMARD) used to treat rheumatoid arthritis (RA).
(2).Tofacitinib acts to block the body's production of enzymes called Janus kinases (JAKs). JAKs play a role in joint inflammation in RA, which can cause pain, swelling and stiffness. If left untreated, RA inflammation could lead to joint erosions, and organ and tissue damage. It may be used alone or in combination with methotrexate or other DMARDs.