Supply High Quality L-Asparaginase L Asparaginase Powder
Product name | L-Asparaginase |
CAS | 9015-68-3 |
Appearance | white powder |
Assay | 99 |
Storage | Cool and Protect from light |
Asparaginase is a kind of enzyme that can be used as a medication and in food industry. It is mainly extracted from E. coli. In the medical field, it can be used for the treatment of acute lymphoblastic leukemia, acute myeloid leukemia, and non-Hodgkin's lymphoma. This is due to that asparaginase can convert the L-asparagine into aspartate and ammonia, exhausting the available asparagine needed for leukemic cells and thus leading to cell death. In the food industry, it can be used as a processing aid in the manufacture of food to reduce the formation of acrylamide, which is a potential carcinogen through removing the asparagine which can undergo Maillard reaction during cooking to induce tumor in fried and baked food.Asparaginase is an enzyme preparation derived from E. coli, a cyclically specific anticarbonic drug that hydrolyzes the serum of asparagine into aspartic acid and ammonia, an amino acid essential for cell protein synthesis and proliferation. Normal cells have their own synthesis function of amino acid, and tumor cells such as acute leukemia, no this function, so when using this product to make the door is missing sharply amino acid, the tumor cells by both neither can get enough from the blood of amino acid, also can not own synthesis, to make the protein synthesis by the obstacle, the proliferation inhibition, much damage cells, rather than growth, survival, reach the role of anti-tumor. This product can also interfere with cell DNA and RNA synthesis, and may act on cell G1 proliferation cycle, as a cell cycle specific drug to inhibit cell division in this period.